Microvascular obstruction after successful fibrinolytic therapy in acute myocardial infarction. Comparison of reteplase vs reteplase+abciximab: A cardiovascular magnetic resonance study

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Microvascular obstruction after successful fibrinolytic therapy in acute myocardial infarction. Comparison of reteplase vs reteplase+abciximab: A cardiovascular magnetic resonance study

BACKGROUND.: About one third of patients with TIMI 3 after reperfusion have evidence of microvascular obstruction (MO) which represents an independent predictor of myocardial wall rupture. This explains all efforts made to prevent MO. Magnetic resonance imaging (MRI) has proved to be particularly useful in detecting MO. The aim of this study was to evaluate with MRI if different fibrinolytic re...

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The prognostic significance of microvascular obstruction after myocardial infarction as defined by cardiovascular magnetic resonance.

Cardiac magnetic resonance imaging (CMR) has evolved into an important imaging tool in the assessment of patients with myocardial infarction (MI), with or without reperfusion. CMR is a gold standard technique for measuring left ventricular volumes and global function. The technique of delayed contrast enhancement has been carefully validated in animal markers as a measure of infarct size. The p...

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Prognostic value at 5 years of microvascular obstruction after acute myocardial infarction assessed by cardiovascular magnetic resonance

BACKGROUND Early and late microvascular obstruction (MVO) assessed by cardiovascular magnetic resonance (CMR) are prognostic markers for short-term clinical endpoints after acute ST-elevation myocardial infarction (STEMI). However, there is a lack of studies with long-term follow-up periods (>24 months). METHODS STEMI patients reperfused by primary angioplasty (n = 129) underwent MRI at a med...

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Magnetic Resonance Imaging Predicts Cardiovascular Outcomes after Acute Myocardial Infarction

Background: Existing data assessing the prognostic value of contrast-enhanced magnetic resonance imaging (ce-CMR) after acute myocardial infarction (AMI) are limited by short followup duration and small cohort sizes. We sought to determine if infarct size and ejection fraction (EF) predict the occurrence of major adverse cardiac events (MACE) after AMI. Methods: We studied 112 patients (mean ag...

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Magnetic resonance imaging-defined areas of microvascular obstruction after acute myocardial infarction represent microvascular destruction and haemorrhage.

AIMS Lack of gadolinium-contrast wash-in on first-pass perfusion imaging, early gadolinium-enhanced imaging, or late gadolinium-enhanced (LGE) cardiovascular magnetic resonance (CMR) imaging after revascularized ST-elevation myocardial infarction (STEMI) is commonly referred to as microvascular obstruction (MVO). Additionally, T2-weighted imaging allows for the visualization of infarct-related ...

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ژورنال

عنوان ژورنال: Heart International

سال: 2006

ISSN: 2036-2579,1826-1868

DOI: 10.4081/hi.2006.54